Roanoke College is located right off of Interstate 81. If you are driving to Roanoke from outside the region, follow these directions:
- From I-81 N Take exit 140. Turn right off of the exit on Thompson Memorial Drive (Route 311).
- Follow VA-311 S/Thompson Memorial Dr to E Clay St.
- Turn right on E Clay St.
- Roanoke College will be on your right.